Abstract: A telemetry navigation system that controls animal-robots based on PC is described.In the system,the control command dictated from the PC can be sent to the controller embedded in the animal-robot,then the controller sends biphasic stimulation pulses to nucleus to control the animal-robot behavior.In addition,the controller can control several brain locations of animal-robots simultaneously,and extend more channels easily;so different brain control experiments as well as other related electrophysiological experiments can be provided.Experiments indicate that the system performs stably with high fidelity and outstanding capability even in complex environments over a distance of about 300 m.Furthermore,the system is small and light so that it can be easily carried by animal-robots.