Abstract: This paper introduces the bi-planar navigation robot system in terms of the bi-planar localization algorithm and a modularized navigation robot.This system could be applied to different orthopedic indications by slightly modifying the mapping algorithm and the structure of navigation robot.The applications of the bi-planar navigation robot system in tibia intramedullary nailing,femur intramedullary nailing,femoral neck cannulated screw and sacro-iliac screw are also introduced in terms of workspace,projection module,localization algorithm,clinical experiments and evaluation indices.