Abstract: The manipulator’s forward and inverse kinematics are analyzed with D-H transformation matrix, and a deviation model for solving the design problem of strain gauge automated assembly system is provided. This method not only avoids global calibration of the system, but also effectively solves the problem of trajectory planning. Meanwhile, the machine vision technology is used to determine the center position of the front actuator, which improves the system positioning accuracy. Prototype test results show that the design goals and requirements are achieved in terms of the speed, accuracy and consistency of strain gauge mounting. The system can be put into the industrial application of automatic mounting of strain gauges. During production process, the system can complete 20 times mounting per minute, and the offset accuracy is less than 0.1 mm, the deflection accuracy is less than 1°.